Adolescent Substance Abuse Epidemiology

The Teen Brain and Alcohol

  1. Brown, S. A., Tapert, S. F., Granholm, E., & Delis, D. C. (2000). Neurocognitive functioning of adolescents: effects of protracted alcohol use. Alcoholism: Clinical and Experimental Research, 24(2), 164-171 PMID 10698367.

  2. Silveri, M. M., & Spear, L. P. (1998). Decreased sensitivity to the hypnotic effects of ethanol early in ontogeny. Alcoholism: Clinical and Experimental Research, 22, 670-676 PMID 9622449.

  3. Tapert, S. F., Schweinsburg, A. D., Bartlett, V. C., Brown, S. A., Frank, L. R., Brown, G. G., & Meloy, M. J. (2004). Blood oxygen level dependent response and spatial working memory in adolescents with alcohol use disorders. Alcoholism: Clinical and Experimental Research, 28, 1577-1586 PMID 15597092.

  4. White, A. M., Truesdale, M. C., Bae, J. G., Ahmad, S., Wilson, W. A., Best, P. J., & Swartzwelder, H. S. (2002). Differential effects of ethanol on motor coordination in adolescent and adult rats. Pharmacol Biochem Behav, 73(3), 673-677. doi:S0091305702008602 [pii] PMID 12151043.

 

Marijuana and the Brain

  1. Devane, W. A., Hanus, L., Breuer, A., Pertwee, R. G., Stevenson, L. A., Griffin, G., … Mechoulam, R. (1992). Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science, 258, 1946-1949 PMID 1470919.

  2. Fattore, L., Fadda, P., Spano, M. S., Pistis, M., & Fratta, W. (2008). Neurobiological mechanisms of cannabinoid addiction. Molecular and cellular endocrinology, 286(1-2 Suppl 1), S97-S107. doi:10.1016/j.mce.2008.02.006 PMID 18372102.

  3. Filbey, F. M., Schacht, J. P., Myers, U. S., Chavez, R. S., & Hutchison, K. E. (2009). Marijuana craving in the brain. Proceedings of the National Academy of Sciences of the United States of America, 106(31), 13016-13021. doi:10.1073/pnas.0903863106 PMID 19651613.

  4. Gessa, G. L., Melis, M., Muntoni, a L., & Diana, M. (1998). Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors. European journal of pharmacology, 341(1), 39-44 PMID 9489854.

  5. Mechoulam, R., & Gaoni, Y. (1965). A total synthesis of DL-delta-1-tetrahydropcannabinol, the active constituent of hashish. Journal of the American Chemical Society, 87, 3273-3275 PMID 14324315.

 

Marijuana and Driving

  1. Asbridge, M., & Hayden, J. A. (2012). Acute cannabis consumption and motor vehicle collision risk?: systematic review of observational studies and meta-analysis, 536(February), 1-9. doi:10.1136/bmj.e536 PMID 22323502.

  2. Grotenhermen, F., Leson, G., Berghaus, G., Drummer, O. H., Krüger, H.-P., Longo, M., … Tunbridge, R. (2007). Developing limits for driving under cannabis. Addiction (Abingdon, England), 102(12), 1910-1917. doi:10.1111/j.1360-0443.2007.02009.x PMID 17916224.

  3. Jones, A. W., Holmgren, A., & Kugelberg, F. C. (2008). Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. Addiction, 103(3), 452-461 PMID 18190663.

  4. Li, M.-C., Brady, J. E., DiMaggio, C. J., Lusardi, A. R., Tzong, K. Y., & Li, G. (2012). Marijuana use and motor vehicle crashes. Epidemiologic reviews, 34(1), 65-72. doi:10.1093/epirev/mxr017 PMID 21976636.

  5. Ramaekers, J. G., Berghaus, G., van Laar, M., & Drummer, O. H. (2004). Dose related risk of motor vehicle crashes after cannabis use. Drug and Alcohol Dependence, 73(2), 109-119. doi:10.1016/j.drugalcdep.2003.10.008 PMID 14725950.

 

Marijuana and the Risk for Schizophrenia and Depression

  1. Bossong, M. G., & Niesink, R. J. M. (2010). Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia. Progress in Neurobiology, 92, 370-385.3 PMID 20624444.

  2. Davis, G. P., Compton, M. T., Wang, S., Levin, F. R., & Blanco, C. (2013). Association between cannabis use, psychosis, and schizotypal personality disorder: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions. Schizophrenia research. doi:10.1016/j.schres.2013.10.018 PMID 24200416.

  3. Malone, D. T., Hill, M. N., & Rubino, T. (2010). Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models. British journal of pharmacology, 160(3), 511-522. doi:10.1111/j.1476-5381.2010.00721.x PMID 20590561.

  1. Hingson, R W, Heeren, T., & Winter, M. R. (2006). Age at drinking onset and alcohol dependence. Archives of Pediatric and Adolescent Medicine, 160, 739-746 PMID 16818840.

  2. Hingson, Ralph W, & Zha, W. (2009). Age of drinking onset, alcohol use disorders, frequent heavy drinking, and unintentionally injuring oneself and others after drinking. Pediatrics, 123(6), 1477-1484. doi:10.1542/peds.2008-2176 PMID 19482757.

  3. International, R. T. I., SAMHSA, & Studies, O. of A. (2010). Results From the 2009 National Survey on Drug Use and Health: Volume I. Summary of National Findings.

  4. Substance Abuse and Mental Health Services Administration, O. of A. S. (2009). Treatment Episode Data Set (TEDS). Highlights – 2007. National Admissions to Substance Abuse Treatment Services. DASIS Series: S-45, DHHS Publication No. (SMA) 09-4360. Rockville, MD.

 

Brain Development during Adolescence

  1. Casey, B. J., Getz, S., & Galvan, A. (2008). The adolescent brain. Dev Rev, 28(1), 62-77 PMID 18688292.

  2. Galvan, A, Hare, T., Parra, C., Penn, J., Voss, H., Glover, G., & Casey, B. J. (2006). Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. Journal of Neuroscience, 26, 6885-6892 PMID 16793895.

  3. Galvan, Adriana, Hare, T., Voss, H., Glover, G., & Casey, B. J. (2007). Risk-taking and the adolescent brain: who is at risk? Developmental science, 10(2), F8-F14. doi:10.1111/j.1467-7687.2006.00579.x PMID 17286837.

  4. Giedd, J. (2004). Structural magnetic resonance imaging of the adolescent brain. Annals of the New York Academy of Sciences, 1021, 77-85 PMID 15251877.

  5. Giedd, J. N. (2008). The teen brain: insights from neuroimaging. Journal of Adolescent Health, 42(4), 335-343 PMID 18346658.

  6. Giedd, J. N., Blumenthal, J., F Jeffries, N. L., Castellanos, F. X., Liu, H., Zijdenbos, A., … Rapoport, J. L. (1999). Brain development during childhood and adolescence: a longitudinal MRI study. Nature Neuroscience, 2, 861-863 PMID 10491603.

  7. Gogtay, N., Giedd, J., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., … Thompson, P. M. (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences, 101, 8174-8179 PMID 15148381.

  8. Lenroot, R. K., & Giedd, J. N. (2006). Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev, 30(6), 718-729. doi:S0149-7634(06)00045-5 [pii] 10.1016/j.neubiorev.2006.06.001 PMID 16887188.

  9. Steinberg, L. (2010). A dual systems model of adolescent risk-taking. Developmental psychobiology, 52(3), 216-224. doi:10.1002/dev.20445 PMID 20213754.

  10. Steinberg, L., Graham, S., O’Brien, L., Woolard, J., Cauffman, E., & Banich, M. (2009). Age differences in future orientation and delay discounting. Child development, 80(1), 28-44. doi:10.1111/j.1467-8624.2008.01244.x PMID 19236391.

 

Vulnerability of the Adolescent Brain to Addiction

  1. Koob, G. F., & Volkow, N. D. (2010). Neurocircuitry of addiction. Neuropsychopharmacology, 35, 217-238 PMID 19710631.

  2. Russo, S. J., Dietz, D. M., Dumitriu, D., Morrison, J. H., Malenka, R. C., & Nestler, E. J. (2010). The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends in neurosciences, 33(6), 267-276. doi:10.1016/j.tins.2010.02.002 PMID 20207024.

  3. Sulzer, D. (2011). How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron, 69(4), 628-649. doi:10.1016/j.neuron.2011.02.010 PMID 21338876.

  4. Volkow, N. D., Fowler, J. S., Wang, G.-J., Swanson, J. M., & Telang, F. (2007). Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Archives of Neurology, 64(11), 1575-1579 PMID 17998440.